Prof. Martin Hrabe de Angelis
Prof. Johannes Beckers
The Helmholtz Zentrum München is the German Research Center for Environmental Health and a member of the Helmholtz Association of German Research Centers. It investigates important common diseases which develop from the interaction of lifestyle, environmental factors and personal genetic background, focusing particularly on diabetes mellitus, allergies and chronic lung diseases.
The aim of the Institute of Experimental Genetics (IEG) is to further the understanding of mechanisms that underlie the etiology of human diseases. Metabolic diseases with focus on diabetes are key areas of research. Experimental set-ups are centered on the mouse as pre-clinical model organism with direct translation of results to humans. Besides studying the effects of genotypes, the institute identifies and characterizes environmental and epigenetic factors and the mechanisms by which these act on the etiology of diseases.
The Group of Epigenetics and Gene Regulation within the IEG focuses its research on the epigenetic inheritance of acquired metabolic traits across generations. We contribute to the goals of GO-DS21 with our long-standing expertise in systemic phenotyping of mouse models and in transcriptomic analyses.